E1 - Synthetic Toad Venom Machine

Aired: January 04, 2021

Haunted by past mistakes, Hamilton embarks on a journey to correct an error in his reporting and identifies the origin of an international toad venom smoking phenomenon.

E2 - A Positive Methamphetamine Story

Aired: January 11, 2021

From X-ray crystallography to vesicular dopamine release, Hamilton travels the country visiting meth labs in order to understand the process behind a great American folk art.

E3 - Xenon: the Perfect Anesthetic?

Aired: January 18, 2021

Hamilton traces the multibillion year history of nitrous oxide on Earth and follows the strangest noble gas to the Czech Republic.

E4 - Synethetic Ibogaine-Natural Tramadol

Aired: January 25, 2021

After revealing a scientific mystery around Tramadol-addicted cows in Central Africa, Hamilton follows a Gabonese opiate addict to a psychedelic ritual.

E5 - Bufotenine: In Search of Hataj

Aired: February 01, 2021

Succumbing to viewer requests, Hamilton journeys to South America to understand the legend of Bufotenine, the world's oldest psychedelic.

E6 - Ultra LSD

Aired: February 08, 2021

With the precise structure of LSD's molecular target identified, Hamilton discusses the new era of psychedelic research and meets pioneers of the field.